ISARIC CCP Toolkit
ISARIC CCP Toolkit
The ISARIC Tools are licensed under a Creative Commons licence. We kindly ask that all research partners who utilise these tools in their projects, publications, or presentations properly acknowledge and cite them. Such recognition is vital to support the continued development, maintenance, and enhancement of the tools. Please use the following citation in your work:
Dunning JW, Merson L, Rohde GGU, Gao Z, Semple MG, Tran D, et al. Open source clinical science for emerging infections. The Lancet Infectious Diseases. 2014;14(1):8-9. Link to the article
Abbas A, Abdukahil SA, Abdulkadir NN, Abe R, Abel L, Absil L, et al. The value of open-source clinical science in pandemic response: lessons from ISARIC. The Lancet infectious diseases. 2021;21(12):1623-4. Link to the article
ARC: doi:10.5281/zenodo.14616571
BRIDGE : Garcia-Gallo E, Duque Vallejo S, Edinburgh T, Pesonel E, Merson L. ISARIC BRIDGE doi:10.5281/zenodo.14162845 https://bridge.isaric.org/
Garcia-Gallo E, Edinburgh T, Bastos L, Peres I, Imtiaz H, Raffaini LE, et al. ISARIC VERTEX. ISARIC; 2024. doi:10.5281/zenodo.14170825
https://github.com/ISARICResearch/VERTEX/
Wellcome Trust [303666/Z/23/Z]
UK International Development [301542-403]
Gates Foundation [INV-063472]
This prospective observational study used data collected in [SITE/LOCATION] through the ISARIC/WHO Clinical Characterisation Protocol for Severe Emerging Infections 1,2. Data capture was conducted using a case report form (CRF) based on ISARIC ARC 3, a structured, machine-readable library of standardised questions designed to support rapid and harmonised data collection across outbreaks. The CRF used for characterization of [DISEASE] during this outbreak was adapted for this specific study context using ISARIC BRIDGE4, a web-based platform that facilitates CRF design and customisation.
Data analysis were generated performed in ISARIC VERTEX5, a web-based application that allows analisis of ISARIC ARC-formatted data and generates tables and visualizations to support key research questions. VERTEX is part of the ISARIC Clinical Epidemiology Platform, developed to standardize and streamline data collection and analysis in outbreak-related clinical research. A public implementation of VERTEX for this study is available at: [Public vertex project webpage adress]
ISARIC is supported by the Wellcome Trust [303666/Z/23/Z]; UK International Development [301542-403]; and the Bill & Melinda Gates Foundation [INV-063472]
REFERENCES
1.Dunning JW, Merson L, Rohde GGU, Gao Z, Semple MG, Tran D, et al. Open source clinical science for emerging infections. The Lancet Infectious Diseases. 2014;14(1):8-9
2.Abbas A, Abdukahil SA, Abdulkadir NN, Abe R, Abel L, Absil L, et al. The value of open-source clinical science in pandemic response: lessons from ISARIC. The Lancet infectious diseases. 2021;21(12):1623-4
3.Garcia-Gallo E, Darji D, Duque-Vallejo S, et al. Data from: ISARIC ARC v1.0.0. 2024. doi:10.5281/zenodo.14113728
4.Garcia-Gallo E, Duque Vallejo S, Edinburgh T, Pesonel E, Merson L. ISARIC BRIDGE. doi:10.5281/zenodo.14162845. https://bridge.isaric.org/
5.Garcia-Gallo E, Edinburgh T, Bastos L, et al. ISARIC VERTEX. doi:10.5281/zenodo.14170824. https://github.com/ISARICResearch/VERTEX/